OpenEvidence vs HealthKey
A side-by-side look at pricing plans, free tiers, features, pros and cons, updated for 2026. OpenEvidence is completely free, while HealthKey is paid.
At a glance
Best for
Pricing model
Starting price
Free plan
Made by
Based in
Rating
Key features
- Cited clinical answers
- Journal content partnerships
- Guideline summaries
- Mobile apps
- Visit documentation
- EHR integration
- Eligibility criteria encoding
- AI prescreening
- Daily candidate emails
- Coordinator review
| Feature | OpenEvidence | HealthKey |
|---|---|---|
| Best for | AI medical search engine that answers clinical questions with citations | AI prescreening that finds eligible patients for clinical trials |
| Category | Legal, finance & HR | Legal, finance & HR |
| Pricing model | Free | Paid |
| Starting price | Free | See pricing page |
| Free plan | Yes, fully free | No |
| Made by | OpenEvidence | HealthKey |
| Based in | United States | – |
| Rating | No ratings yet | No ratings yet |
| Key features |
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Pricing compared
OpenEvidence is completely free, while HealthKey is paid.
Free plan
Cheapest paid plan
Top plan
Free trial
Prices in USD, checked Oct 28, 2026 or later. Plans change often, so confirm on each tool's site before you buy.
Pros and cons
OpenEvidence
- Free for verified clinicians
- Answers link to studies
- Fast point-of-care lookups
- Full access needs US verification
- Ad-supported model
- Not a substitute for judgement
HealthKey
- Daily list of eligible patients
- Humans review each match
- Aims to reduce screen failures
- Requires EHR integration
- Pricing is not shown on the homepage
- Built only for trial sites
Which one should you choose?
Choose OpenEvidence if you want:
- Free for verified clinicians
- Answers link to studies
- Fast point-of-care lookups
Watch out: full access needs us verification.
Choose HealthKey if you want:
- Daily list of eligible patients
- Humans review each match
- Aims to reduce screen failures
Watch out: requires ehr integration.
OpenEvidence vs HealthKey FAQ
What is the difference between OpenEvidence and HealthKey?
OpenEvidence: AI medical search engine that answers clinical questions with citations. HealthKey: AI prescreening that finds eligible patients for clinical trials. Both are legal, finance & hr tools.
Is OpenEvidence or HealthKey cheaper?
OpenEvidence is completely free, while HealthKey is paid.
Do OpenEvidence and HealthKey have free plans?
OpenEvidence: Yes, fully free. HealthKey: No.
Who makes OpenEvidence?
OpenEvidence is made by OpenEvidence, based in United States.
Who makes HealthKey?
HealthKey is made by HealthKey.
Which should I choose, OpenEvidence or HealthKey?
Choose OpenEvidence if you value free for verified clinicians and answers link to studies. Choose HealthKey if you value daily list of eligible patients and humans review each match.